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Weichteilsarkom: Studien

SU2C-SARC032

Pembrolizumab, radiation therapy,and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity

Sarkom-Studie Randomisierte Phase II-Studie zum Einsatz von liposomalem Doxorubicin (Myocet) plus Ifosfamid versus Doxorubicin plus Ifosfamid in der Primärtherapie des lokal fortgeschrittenen oder metastasierten Weichteilsarkoms
SUCCEED Testung des mTOR-Inhibitor Ridaforolimus
PALETTE

Testung eines VEGF-Rezeptor-IH

SAREZ

„SAREZ- SArkom REZidivregister Sarcoma Relapse Registry for relapsed sarcoma of bone and soft tissues“

EORTC-STBSG 62012

Doxorubicin alone versus doxorubicin plus ifosfamide for first line treatment of advanced or metastatic soft-tissue sarcoma.

EORTC-STBSG 62961 Bei high-risk Weichteilsarkomen im Erwachsenenalter verbessert eine Hyperthermie das Ergebnis einer präoperativen EIC-Chemotherapie.
EORTC 62092-22092

Preoperative radiotherapy plus surgery versus surgery alone for patients with retroperitoneal sarcomas

RTOG-0630

Significant Reduction of Late Toxicities in Patients With Extremity Sarcoma Treated With Image-Guided Radiation Therapy to a Reduced Target Volume

Trabectedin- Studie

Trabectedin or cacarbazine for metastatic liposarcoma or leiomyosarcoma after failure of conventional chemotherapy.

French Sarcoma Group

LMS04

Combination therapy with doxorubicin and trabectedin induction, followed by trabectedin maintenance, was associated with improved overall survival and progression-free survival, as compared with doxorubicin alone, among patients with metastatic or surgically unresectable uterine or soft-tissue leiomyosarcoma.(1)

Teil von

 Weichteilsarkome Sarkome und gutartige Weichteiltumoren Onkologie
Quellen 1.) Pautier P, et al. for the French Sarcoma Group:
Doxorubicin–Trabectedin with Trabectedin Maintenance in Leiomyosarcoma.
N Engl J Med 2024;391:789-99.
DOI: 10.1056/NEJMoa2403394

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