Brustkrebs - Screening: Studien
Vor Einführung von Screeningprogrammen wurden große Studien durchgeführt.
Mammography Screening of Young Women
Die Brustkrebs-Sterblichkeit von Frauen 40-49 Jahre kann durch Mammographie-Screening gesenkt werden.
| Studie | Patienten | Alter | Follow-up | Relatives Mortalitätsrisiko |
| New York, HIP 1963 | 60.000 | 40-64 | 18 | 0,77(0,61-0,97) |
| BCDDP | ||||
| Frischbier-Studie, Hamburg | ||||
| Swedish Two- County Trial 1977 | 130.000 | 40-74 | 11 | 0,69 (0,58-0,80) |
| Canada (CNBSS) 1980 | 50.000 | 40-49 | 11-16 | 1,06 (0,80-1,40) |
| 40.000 | 50-59 | 7 | 0.97 (0,62-1,52) | |
| Malmö 1976 | 40.000 | 45-69 | 9 | 0,96 (0,68-1,35) |
| Stockholm 1981 | 60.000 | 40-64 | 7,4 | 0,71 (0,4-1,2) |
| Gothenburg 1982 | 50.000 | 39-59 | 12-14 | 0,79 (0,58-1,08) |
| Edinburgh 1978 | 45.000 | 45-64 | 7 | 0,83 (0,58-1,18) |
| UK Age Trial 1991 | 160.000 | 39-48 | 10 | 0,83 (0,66-1,04) |
| DMS |
| Studie | Alter bei Studienbeginn |
Regim | Intervall / Monate |
Runden | Follow-up/Jahre | RR | CI 95% |
| HIP (1963-69) | 50-59 | 2v, CBE | 12 | 4 | 6 10 18 |
0,46 0,69 0,77 |
(0.25-0.84) (0.46-1.02) (0.55-1.08) |
| Malmö (1976-86) | 55-69 | 1 or 2v | 18-24 | 5 | 8.8 12 |
0.79 0,82 |
(0.51-1.24) (0.57-1.19) |
| Two-county (1977-85) | 50-74 | 1v | 33 | 4 | 6 8 11 |
0.61 0,60 0,63 |
(0.44-0.84) (0.40-0.90) (0.45-0.88) |
| Edinburgh (1979-88) | 50-64 | 1 or 2v | 24 | 4 | 10 | 0.80 0,85 |
(0.54-1.17) (0.62-1.15) |
| Stockholm (1981-85) | 50-64 | 1v | 28 | 2 | 7.4 11 |
0.57 0,62 |
(0.30-1.10) (0.38-1.00) |
| Studie | Regim | Intervall / Monate |
Runden | Follow-up/Jahre | Eingeladen | Kontrollen | RR | CI 95% |
| HIP (1963-69) | 2v, CBE | 12 | 4 | 18 | 14432 | 14701 | 0.77 | (0.53-1.11) |
| Malmö (1976-86) | 1 or 2v | 18-24 | 5 | 12 | 3658 | 3679 | 0.51 | (0.22-1.17) |
| Kopparberg (1977-85) | 1v | 24 | 4 | 13 | 9582 | 5031 | 0.73 | (0.37-1.41) |
| Östergötland (1977-85) | 1v | 24 | 4 | 13 | 10262 | 10573 | 1.02 | (0.52-1.99) |
| Edinburgh (1979-88) | 1 or 2v | 24 | 4 | 10 | 5913 | 5810 | 0.78 | (0.46-1.31) |
| Stockholm (1981-85) | 1v | 28 | 2 | 7.4 11 |
14 375 | 7103 | 1.09 1,08 |
(0.40-3.00) (0.54-2.17) |
| Gothenburg (1982-88) | 2v | 18 | 4 | 7 | 10600 | 12800 | 0.73 | (0.27-1.92) |
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