zurück Home | postoperative Bestrahlung des Endometriumkarzinoms: Ergebnisse Kucera / Wien 1989 | |||||||||||||||||||||||||||||||||
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Patientinnen | Krankengut der 1. Universitäts-Frauenklinik Wien 1981-1988 | |||||||||||||||||||||||||||||||||
Tumoren | 1001 Frauen mit Endometriumkarzinom wurden postoperativ bestrahlt. | Davon waren 787 im Stadium I. | ||||||||||||||||||||||||||||||||
Altersverteilung |
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Brachytherapie | Alle Frauen erhielten 6 Wochen post OP eine Brachytherapie mit 7Gy in 2cm von der Applikatorachse. | 2 Behandlungen im Abstand von 1 Woche mit Iridium-192. Applikatoroberfläche 32Gy, 7,5mm Gewebetiefe: 14Gy | ||||||||||||||||||||||||||||||||
perkutane Bestrahlung | Indikation im Stadium I: Myometrane Infiltration > 1/3 und Grading > 1 | Telekobalt-Bestrahlung des kleinen Beckens.Biaxiale Pendelung. 56Gy an der Beckenwand, 54Gy in Beckenmitte30 Fraktionen | ||||||||||||||||||||||||||||||||
Ergebnis |
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Quellen |
1.) Kucera H, Vavra N, Weghaupt K: Zum Wert der postoperativen Bestrahlung beim Endometriumkarzinom im histopathologischen Stadium I. Geb Fra 49(1989):618-624 Aalders, J., V. Abeler, P Kolstadt, M. Onsrud: Postoperative external irradiation and prognostic parameters in stage I endometrial carcinoma. Clinical and histopathologic study of 540 patients. Obstet. Gynec. 56 (1980), 419. Bedwinek, J., A. Galakatos, M. Camel, M. Kao, St. Stokes, C. Perez: Stage I, grade III adenocarcinoma of the endometrium treated with surgery and irradiation. Cancer 54 (1984), 40-47. Berman, M. L., S. C. Ballon, L. D. Lagasse, W. G. Watring: Prognosis and treatment of endometrial cancer. Am. J. Obstet. Gynecol. 136 (1980), 679-688. Boronow, R. C.: Endometrial cancer and endometrial hyperplasy. In: Rutledge, F, R. C. Boronow, J. T. Wharton (eds.): Gynecologic oncology. Wiley and Sons, New York 1976 Christopherson, W. M., P. J. Connely, R. C. Alberhasky: Carcinoma of the endometrium. An analysis of prognosticators in patients with favorable subtypes and stage I disease. Cancer 51 (1983), 1705-1709. Creasman, W. T.: Endometrial cancer: Pathogenesis and its implications. XI FIGO World Congress, Berlin 1985. Disaia, P J., W T. Creasman, R. C. Boronow, J. A. Blessing: Risk factors and recurrent patterns in stage I endometrial cancer. Am. J. Obstet. Gynecol. 151 (1985), 1009-1015. Eifel, P., J. Ross, M. Hendrickson, R. S. Cox, R. Kempson, A. Martinez: Adenocarcinoma of the endometrium. Analysis of 256 cases with disease limited to the uterine corpus: Treatment comparisons. Cancer 52 (1983), 11026-11031. Fletcher, G. H., F N. Rutledge, L. Delclos: Adenocarcinoma of the uterus. In: Fletcher, G. H. (ed.): Textbook of radiotherapy. Lea & Febiger, Philadelphia 1973. Frischkorn, R.: Die Nachbestrahlung des operierten Zervix- und Endometriumkarzinoms. Arch. Gynec. 232 (1981), 175. Goodman, R., R. Hellman: The role of postoperative irradiation in carcinoma of the endometrium. Gynec. Oncol. 2 (1974), 354. Gorges, K., H. Vahrson: Prophylaktische Radiumbestrahlung der Vagina. Arch. Gynäk. 219 (1975), 179. Graham, H.: The value of preoperative or postoperative treatment by radium for carcinoma of the uterine body. Surg. Gynec. Obstet. 132 (1971), 855. Green, N., R. W. Methye, J. Kernen: Stage I well differenciated adenocarcinoma of the endometrium. Amer. J. Roentgenol. 123 (1975), 563. Heymann, J.: The radiumhemmet experience in postoperative radiological treatment of cancer of the corpus uteri. Acta radiol. (Stockh.) 18 (1937), 93. Hording, U., U. Hansen: Stage I endometrial carcinoma: A review of 140 patients primarily treated by surgery only. Gynecol. Oncol. 22 (1985), 51-58. Kucera, H., R. Sagl, W Skodler, K. Weghaupt: Die AfterloadingKurzzeitbestrahlung der Scheide nach Radikaloperation des Korpuskarzinoms. Geburtsh. u. Frauenheilk. 46 (1986), 685-689. Kucera, H., W Skodler, K. Weghaupt: Komplikationen der postoperativen Strahlentherapie beim Korpuskarzinom. Geburtsh. u. Frauenheilk. 44 (1984), 498. Kucera, H., K. Weghaupt: Die postoperative Bestrahlung des Carcinoma corporis uteri mit der Iridium-Afterloading-Technik. Strahlentherapie und Onkologie 164 (1988), 501-507. Ladner, H. P.: Zur Prognose und Strahlentherapie des Korpuskarzinoms. Radiologie 23 (1983), 12. Leibel, S. A., M. D. Wharham: Vaginal and para-aortic lymphnodes in carcinoma of the endometrium. Int. J. Radiat. Oncol. Biol. Phys. 6 (1980), 893-914 Malkasian, G. D., J. F Annegers, K. S. Fountain: Carcinoma of the endometrium: Stage I. Am. J. Obstet. Gynecol. 136 (1980), 872-888. Mandell, L., N. Dattatreyudu, L. Anderson, B. Hillaris: Postoperative vaginal radiation in endometrial cancer using a remote afterloading technique. Int. J. Radiat. Oncol. Biol. Phys. 11 (1985), 473-478. Marchetti, D. L., M. S. Piver, Y. Tsukada, P Reese: Prevention of vaginal recurrence of stage I endometrial adenocarcinoma with postoperative vaginal radiation. Obstet. Gynec. 67 (1986), 399-402. Morrow, C. P., D. E. Townsend: Cancer of the uterine corpus. In: Synopsis of gynecologic oncology. Wiley and Sons, New York 1981. Onsrud, M., P Kolstad, T. Normann: Postoperative external pelvic irradiation in carcinoma of the corpus stage I. A controlled clinical trial. Surg. Oncol. 4 (1976), 222. Piver, M. St., R. Yazigi, L. Blumenson, Y. Tsukada: A prospective trial comparing hysterectomy, hysterectomy plus vaginal radium and uterine radium plus hysterectomy in stage I endometrial carcinoma. Obstetrics & Gynecology 54 (1979), 85-89. Thigpen, J. T., C. P Morrow, J. A. Blessing: Adjuvant chemotherapy in high-risk endometrial carcinoma. The Gynecologic Oncology Group experience. In: Bolla, M. et al. (eds.) Endometrial cancers. Karger, Basel pp. 223-232, 1986. Wall, J. C., H. Lochmüller: Präoperative Kontaktbestrahlung beim Endometriumkarzinom. Geburtsh. und Frauenheilk. 42 (1982), 394 Whetham, J. C., G. L. Bean: Carcinoma of the endometrium. Amer. J. Obstet. Gynec. 112 (1972), 339. |
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